Cristiano Ronaldo is to leave Manchester United by mutual agreement, with immediate effect, the club announced on Tuesday.
In a statement put on its website, the club said: "Cristiano Ronaldo is to leave Manchester United by mutual agreement, with immediate effect.
"The club thanks him for his immense contribution across two spells at Old Trafford, scoring 145 goals in 346 appearances, and wishes him and his family well for the future.
"Everyone at Manchester United remains focused on continuing the team's progress under Erik ten Hag and working together to deliver success on the pitch."
Ronaldo in response stated, "Following conversations with Manchester United we have mutually agreed to end our contract early.
"I love Manchester United and I love the fans, that will never ever change. However, it feels like the right time for me to seek a new challenge.
"I wish the team every success for the remainder of the season and for the future."
Reports last week claimed United's lawyers had been looking at ways to bring Ronaldo's time at the club to an end in the wake of his interview with Piers Morgan on TalkTV.
Ronaldo, who has been a regular on the bench this season - scoring three goals in 16 appearances - accused United of betraying him by trying to force him out of the club.
He also said he had "no respect" for the manager, Erik ten Hag, and alleged two senior figures at Old Trafford treated him with suspicion when he said his daughter Bella was sick with bronchitis, three months after her twin brother died.